Madonna's biggest hits include "Papa Don't Preach," "Like a Prayer" and "Vogue."
The two girls are clearly taking after their mother in the musical department...
The 58-year-old adopted the four-year-old twins from Malawi in February, to join her family.
The 58-year-old posted the adorable video of the girls playing with their new toys to her nine million followers on Instagram, stating: "What happens when you get your first Barbie Doll!
Pikachu is left in the dust!"
The clip isn't the first footage of the young ladies showing off their singing talents, as proud mother Madge has previously posted a video of the girls singing the nursery rhyme 'Twinkle Twinkle Little Star.'
Madonna is already mother to Lourdes, 19, her daughter with ex Carlos Leon, son Rocco, 15, from her marriage to Guy Ritchie, and David Banda, 11, and Mercy, also 11, whom she adopted.