The singer made the decision so he can be with his son who is currently undergoing chemotherapy.
Queen musical We Will Rock You is set to close on London's West End after 12 years, it has been announced
Ben Elton's stage show, which we should never forget was produced by Robert De Niro, will end its long run on May 31, 2014 at the Dominion Theatre.
The show has played to over 6.5 million people at the venue, which is its longest-running show ever. It is also one of the top ten longest-running musicals in West End history.
Opening in May 2002, the musical won five awards at the Theatregoers Choice awards, and was handed the Olivier Audience Award in 2011.
Co-creators Brian May, Roger Taylor and Ben Elton said in a statement: "We want to thank every one of the many hundreds of incredible musical theatre artists, musicians and crew with whom we've had the privilege of working at the Dominion since 2002 - and, of course, the incredible audiences who have rewarded them with over four and a half thousand standing ovations!"
Dominion Theatre manager David Pearson added: "It has been a privilege to have hosted We Will Rock You for the past 12 years. To have the show rocking the Dominion and seeing a standing ovation night after night has been quite amazing.
"We wish the show every success for the future, as we now prepare to accelerate our restoration and refurbishment programme ready to welcome an exciting new production in 2015."
Watch Queen's Bohemian Rhapsody video below: